Introduction to Gamma-Butyrolactone

Gamma Butyrolactone supplier

Gamma-Butyrolactone (GBL) is a synthetic chemical that is widely used for industrial purposes. In appearance, it is a colorless oily liquid and said to have a bitter taste with faint to pleasant odor. Gamma Butyrolactone Suppliers trade this chemical in hundreds and thousands of metric tons for industrial use. 

What is the chemical description of Gamma-Butyrolactone?

GBL, simply, is a lactone as its name implies. It is hydrolyzed under basic conditions. It is readily converted both chemically and in the body to Gamma Hydroxybutyrate (GHB). In fact, one can convert GBL into GHB with plain tap water without additional adjustments. 

When GBL enters blood, it is readily converted to GHB by lactonase enzymes found in the blood. Since GBL is more lipophilic (fat soluble), it is more readily absorbed in humans and has higher bioavailability. 

What are the applications of Gamma-Butyrolactone?

Various companies and businesses around the world, including the UK, the USA, and China stay in touch with Gamma Butyrolactone Suppliers because this chemical has widespread industrial use. It is a common solvent used in:

  • Nail paint removers
  • Paint strippers
  • Stain removers
  • Circuit board cleaners
  • Production of Pyrrolidones
  • Pharmaceuticals 

Besides, it is also used in laboratories for scientific research.

Is the Trade and Production of Gamma Butyrolactone Restricted?

Till now, there is no approved medical use for this chemical. Neither GBL is included in the WHO’s list of essential medicines, nor GBL itself is authorized as a medicine. So, you cannot order this chemical in the name of a medicine as it is not ethical and legal. 

Since GBL is found to cause a state of dependence and can produce similar effects as the Schedule II compound, GHB,  some of the Member States and the European Community have taken voluntary measures to prevent its diversion and reduce the illicit use of this chemical. 

While GBL is sold in health food stores and even athletic venues as a dietary supplement and purported to induce sleep, release growth hormone, and enhance sexual activity and athletic performance, there is no such recognized therapeutic indication for this chemical. Thus, it must be avoided for these purposes as well.

There is no also stated use of this chemical in animal/veterinary care. 

However, production and supply of this chemical for industrial use is permitted. The use of GBL is controlled under legislation that is intended to regulate its availability. 

Are there any side-effects or withdrawal symptoms of Gamma-Butyrolactone when ingested?

Yes, there are many. Some of the adverse effects of ingesting this chemical are vomiting, urinal and fecal incontinence, agitation, convulsions, loss of consciousness, respiratory depression, bradycardia, and coma progressing to death. 

When it is used for a long time, it also leads to withdrawal symptoms, such as tremor, hallucinations, tachycardia, insomnia, seizures, and rhabdomyolysis. There are also some cases that reported that GBL was the reason of death.

Thus, one must not use this chemical for recreational purposes. 

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